D-STEM MUTATION IN AN ESSENTIAL TRNA INCREASES TRANSLATION SPEED AT THE COST OF FIDELITY.


Chronic Exposure to Both Electronic and Conventional Cigarettes Alters Ileum and Colon Turnover, Immune Function, and Barrier Integrity in Mice

Although the effects of cigarette smoke (CS) on the development of several intestinal diseases is well documented, the impact of e-cigarette aerosol (e-cig) on digestive health is largely unknown.To compare the effects of e-cig and CS on mouse ileum and colon, animals were chronically exposed for 6 months by nose-only inhalation to e-cig at 18 or 3

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Mild replication stress causes premature centriole disengagement via a sub-critical Plk1 activity under the control of ATR-Chk1

Abstract A tight synchrony between the DNA and centrosome cycle is essential for genomic integrity.Centriole disengagement, which licenses centrosomes for duplication, occurs normally during mitotic exit.We recently demonstrated that mild DNA replication stress typically seen in cancer cells causes premature centriole disengagement in Protein Snack

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Offensive Weapons of the Akkoyunlu Army

The study aims to clarify the offensive weapons used by the military units of the Akkoyunlu state on the battlefield, to determine the technical characteristics of these weapons, and to reveal the areas of their use by the warriors.The research was carried out based on first-hand sources of the period, and the scientific basis of other scientific s

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